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Abstract Introduction Patients with influenza A H1N1 v infection have reverse transcriptase-polymerase-chain-reaction RT PCR developed rapidly progressive lower respiratory tract disease assay. We describe the clinical and Results Illness onset of the 32 patients occurred between 23 epidemiologic characteristics of the first 32 persons reported to June and 31 July, Ten Twenty-nine Influenza A pneumonia.

Twenty-four patients Oseltamivir frequently observed severe hypoxemia and a relatively high administration delay ranged from 2 to 8 days after illness onset, case-fatality rate. Clinicians should be aware of pulmonary H1N1 testing , cases of influenza A H1N1 v infection, of was performed in each institution or centralized in a reference which were fatal [1]. A Centers for Disease Control and ture [7]. Only 'confirmed cases' were included in the current Prevention CDC report in May provided details of the study.

Secondary bacterial pneumonia was con- UK [5]. This report summarizes the clinical characteris- duction of purulent sputum plus positive bacterial respiratory tics of a series of the first 32 patients reported to this ICU reg- or blood cultures [9] Bronchoalveolar lavage was not system- ister, with special interest in those developing severe atically performed because of the high risk of generating aero- respiratory failure.

Respiratory cultures were based on tracheal aspirates obtained immediately after intubation. Acute renal failure was Materials and methods defined as the need for renal replacement therapy following Data abstracted for this study were obtained from a voluntary the International Consensus Conference [10]. Data were reported by the attend- ing physician reviewing medical charts, radiologic and labora- The following information was recorded: demographic data, tory records.

The consecutive initial reports notified until 1 comorbidities, time of illness onset and hospital admission, August, were eligible for this study. Children under 15 time to first dose of antiviral delivery, microbiologic findings, years old were not enrolled in this registry. Patient identification ment techniques and laboratory finding at ICU admission remained anonymous and informed consent was waived due were also recorded.

All tests and score [11] was determined in all patients within 24 hours of procedures were ordered by the attending physicians. ICU admission. Discrete variables are expressed as counts therapy. For the demographic and clinical characteristics of the One patient 3.

In patients, differences between groups were assessed using addition, 11 patients Secondary superinfection with Pseudomonas iables and the Student's t-test or Mann-Whitney U test for con- aeruginosa were documented in three patients 9. Survival analysis was performed by Kaplan- one presented with invasive candidiasis.

Mean delay between Meier survival distribution. A P value of 0. Signs at physician presen- SOFA score was 7. Data from 32 adults in 20 hospitals were reported to be These patients were later confirmed to have the virus through further Table 1 determination of tracheal secretions.

The baseline characteris- tics of patients are shown in Table 2. Only one patient 3. Ten patients Hematologic disease 1 None 15 Extracorpor- patients C-reactive teristics of patients according to ventilatory support required protein was assessed in 12 patients Eight patients Pero, si lo hubieras leido con la mentalidad de leer un excitante hentai, ahi es cuando sientes el dolor de la protagonista.

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